What is Valaciclovir ?
Valaciclovir, also called as valaciclovir hcl, is an oral antiviral drug used to treat viral infections caused by herpes viruses in adults and children including genital herpes, cold sores, shingles (herpes zoster) and chickenpox. Besides these uses, it is also approved for the treatment of herpes in people who are HIV-positive. Valaciclovir hcl is used to treat cold sores in children above 12 years old, and chickenpox in children above 2 years old. Furthermore, it is also used to treat outbreaks of genital herpes and to reduce the number of future episodes in people with frequent outbreaks. It cannot cure herpes completely, but it can heal current sores and control future sores from developing. For best results Valaciclovir should be taken as soon as the sign or symptoms of herpes appear.
Valaciclovir Manufacturing & Prices
Valaciclovir or Valaciclovir hcl is marketed by GlaxoSmithKline under the trade names Valtrex and Zelitrex. In the United States valaciclovir is marketed in generic form by Ranbaxy Laboratories. Valaciclovir is available in the form of 500 mg and 1 gram tablets. Although the branded version of the pills is overly expensive, generic medication can now be found at low prices, without sacrificing quality and results. On the following website, you will be able to witness the online discount price of Valaciclovir (The numbers are for reference only, as prices may fluctuate):
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Valaciclovir Mode of Action
Valaciclovir is a prodrug that is metabolized in the body to produce the active agent acyclovir and L-valine by way of viral thymidine kinase. Acyclovir (the active metabolite of valaciclovir) antiviral activity is greatest against both types of herpes (HSV-1 and HSV-2 virus), varicella-zoster virus, Epstein-Barr virus and cytomegalo virus. Aciclovir is converted into a monophosphate form. This monophosphate form is further phosphorylated into the active triphosphate form, aciclo-GTP. The virus embedded enzymes can hardly breakdown aciclo GMP from the sequence, leading to a blocked DNA polymerase release.
